"The World Drug Report provides an annual overview of the major developments in drug markets for the various drug categories, ranging from production to trafficking, including development of new routes and modalities, as well as consumption. Chapter 1 of the World Drug Report 2014 provides a global overview of the latest developments with respect to opiates, cocaine, cannabis and amphetamines (including “ecstasy”) and the health impact of drug use. Chapter 2 zeroes in on the control of precursor chemicals used in the manufacture of illicit drugs. On the basis of comprehensive information on supply, as well as the relatively limited new information on demand, it can be concluded that overall the global situation with regard to the prevalence of illicit drug use and problem drug use1 is generally stable, with the total global number of drug users increasingly commensurate with the growth of the world population. That said, each region exhibits its own peculiarities with respect to specific drugs. Polydrug use, which is generally understood as the use of two or more substances at the same time or sequentially, remains a major concern, both from a public health and a drug control perspective. remains stable at between 16 million and 39 million people. However, there continues to be a gap in service provision, as in recent years, only one in six problem drug users globally have had access to or received drug dependence treatment services each year. Although the general public may perceive cannabis to be the least harmful illicit drug, there has been a noticeable increase in the number of persons seeking treatment for cannabis use disorders over the past decade, particularly in the Americas, Oceania and Europe. Nonetheless, opiates remained the most prevalent primary drug of abuse among those seeking treatment in Asia and in Europe, as did cocaine in the Americas. With regard to injecting drug use, the United Nations Office on Drugs and Crime (UNODC), the Joint United Nations Programme on HIV/AIDS (UNAIDS), the World Bank and the World Health Organization (WHO), drawing on the most recent data available, jointly estimate that the number of people who inject drugs is 12.7 million (range: 8.9 million-22.4 million). That corresponds to a prevalence of 0.27 per cent (range: 0.19-0.48 per cent) of the population aged 15-64.2 The problem is particularly stark in Eastern and South-Eastern Europe, where the rate of injecting drug use is 4.6 times higher than the global average..."