Description:
Abstract: "A cross-sectional descriptive study was carried out at a tuberculosis center, Yangon,
Myanmar from October 2003 to July 2004 to analyze the drug susceptibility of new sputum
smear positive pulmonary tuberculosis patients. A total of 202 Mycobacterium tuberculosis
isolates were tested for resistance to isoniazid, streptomycin, rifampicin and ethambutol. Resistance
to at least one anti-tuberculosis drug was documented in 32 (15.8%) isolates. Monoresistance
(resistance to one drug) was noted in 15 (7.4%) isolates and poly-resistance (resistance
to two or more drugs) was noted in 17 (9.4%) isolates, including 8 (4.0%) multi-drug
resistant isolates (resistance to at least isoniazid and rifampicin). Total resistance to individual
anti-tuberculosis drugs were: isoniazid (29, 14.3%), streptomycin (11, 5.4%), rifampicin (10,
4.9%) and ethambutol (1, 0.5%). The demographic data and possible contributing factors of
drug resistance were evaluated among the drug resistant patients. Poly-resistant cases had
significantly longer intervals between symptom appearance and achieving effective anti-tuberculosis
treatment than mono-resistant cases (p = 0.015)."
Source/publisher:
SOUTHEAST ASIAN J TROP MED PUBLIC HEALTH Vol 38 No. 1 January 2007
Date of Publication:
2007-01-00
Date of entry:
2010-01-30
Grouping:
- Individual Documents
Category:
Language:
English