Since the World War II, Myanmar better known the world over as Burma, had never attracted so much international attention as now. Actually, there are reasons both global and local for this development. The rise of China as a major global economic power and the unlocking of India?s potential to grow as yet another global economic power are redefining international relationships in South and Southeast Asia. Myanmar is now viewed as a critical area of interest to China and India. It is of special interest to the U.S. which would like to check the over riding influence of China in this region while cruising on its journey to the status of a contending global power. While China has developed close political, military and economic relations with Myanmar, India is in the process of following suite. A study of India-Myanmar and Sino-Myanmar relations offer some interesting aspects of how they are adopting the geo-strategic setting and political environment of the region to their advantage.